A gene-edited macaque which researchers knocked out BMAL1, a core circadian regulatory transcription factor, interacts with a staff member at the Institute of Neuroscience of Chinese Academy of Sciences in Shanghai, east China, Jan. 22, 2019. China has cloned five monkeys from a gene-edited macaque with circadian rhythm disorders, the first time multiple monkeys have been cloned from a gene-edited monkey for biomedical research. (Xinhua/Jin Liwang)